RKL-HM001-100μg / 询价
RKL-HM001-500μg / 询价
RKL-HM001-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant Human RANKL/TNFSF11/CD254 Protein is expressed from HEK293 without tag. It contains Gly63-Asp244.[Accession | O14788-2] |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 20.5 kDa. Due to glycosylation, the protein migrates to 30-60 kDa based on Tris-Bis PAGE resu |
内毒素(Endotoxin)
|
Less than 1EU per μg by the LAL method. |
纯度(Purity)
|
> 90% as determined by Tris-Bis PAGE |
制剂(Formulation)
|
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
重构方法(Reconstitution)
|
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
存储(Storage)
|
-20 to -80°C for 12 months as supplied from date of receipt. |
Recombinant Human RANKL/TNFSF11/CD254 Protein is expressed from HEK293 without tag. It contains Gly63-Asp244.[Accession | O14788-2]
The protein has a predicted MW of 20.5 kDa. Due to glycosylation, the protein migrates to 30-60 kDa based on Tris-Bis PAGE resu
Less than 1EU per μg by the LAL method.
> 90% as determined by Tris-Bis PAGE
> 90% as determined by HPLC
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3-6 months after reconstitution.
2-8°C for 2-7 days after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone.
ODF; OPGL; RANKL; TRANCE; CD254; sOdf; TNFSF11; OPTB2
(1) Nagy V, Penninger JM. The RANKL-RANK Story. Gerontology. 2015;61(6):534-42. doi: 10.1159/000371845. Epub 2015 Feb 14. PMID: 25720990.
RKL-HM001-100μg / 询价
RKL-HM001-500μg / 询价
RKL-HM001-500μgx2 / 询价
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